InRegPep predicting peptide aggregates with parallel in-register structure

InRegPep assembler is an online server for modeling aggregates formed by amyloidogenic peptides that favor in-register, parallel β-sheet architectures. Given a user-submitted amino acid sequence, the server generates a set of plausible 3D aggregate models and proposes protofilament-like arrangements. These results provide the groundwork for further structural studies, including analyses of conformational polymorphism, mutational design, and downstream experimental or computational validation.




















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