{"id":12,"date":"2019-07-10T14:27:56","date_gmt":"2019-07-10T14:27:56","guid":{"rendered":"https:\/\/dworkowa.imdik.pan.pl\/new\/?page_id=12"},"modified":"2026-01-19T12:23:17","modified_gmt":"2026-01-19T11:23:17","slug":"home","status":"publish","type":"page","link":"https:\/\/bioinfo.imdik.pan.pl\/","title":{"rendered":"Home"},"content":{"rendered":"\r\n<p>We develop and apply multi-scale molecular and integrative modeling methods to study complex molecular systems, along with bioinformatics and biomedical informatics techniques. Our research focuses on:<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n\r\n\r\n<li>multi-scale modeling of protofilament and amyloid fibril self-assembly,<\/li>\r\n\r\n\r\n\r\n<li>identifying enzymatic cleavage sites in peptide and protein substrates,<\/li>\r\n\r\n\r\n\r\n<li>investigating the structure, dynamics, and signaling of GPCRs,<\/li>\r\n\r\n\r\n\r\n<li>predicting protein structures and studying protein-protein interactions,<\/li>\r\n\r\n\r\n\r\n<li>molecular modeling of biological membranes,<\/li>\r\n\r\n\r\n\r\n<li>using molecular docking for drug design and discovery,<\/li>\r\n\r\n\r\n\r\n<li>analyzing the spatial structures of biopolymers and applying deep learning techniques in structural biology.<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p><strong>Grants:<\/strong><\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li><strong>2026-2027<\/strong>: 2025\/57\/B\/NZ1\/03117 &#8220;Identification of proteolytic cleavage sites in peptide substrates using coarse-grained docking and machine learning methods&#8221;,<\/li>\r\n<li><strong>2022-2026<\/strong>: 2021\/43\/B\/NZ2\/02082 &#8220;Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simulations&#8221;,<\/li>\r\n\r\n\r\n\r\n<li><strong>2012-2017<\/strong>: 2011\/03\/D\/NZ2\/02004 &#8220;Analysis of similarity of biopolymer structures using descriptors of local structure\u201d,<\/li>\r\n\r\n\r\n\r\n<li><strong>2014-2016<\/strong>: IP2012016372 &#8220;Study of signaling of&nbsp; GPCRs using multi-scale molecular dynamics simulations&#8221;,<\/li>\r\n\r\n\r\n\r\n<li><strong>2012-2016<\/strong>: 2011\/01\/D\/NZ2\/05314 &#8220;Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the ligand-induced alternations of the receptor structure&#8221;.<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p><\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>We develop and apply multi-scale molecular and integrative modeling methods to study complex molecular systems, along with bioinformatics and biomedical informatics techniques. Our research focuses on: Grants:<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-12","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/pages\/12","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/comments?post=12"}],"version-history":[{"count":16,"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/pages\/12\/revisions"}],"predecessor-version":[{"id":613,"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/pages\/12\/revisions\/613"}],"wp:attachment":[{"href":"https:\/\/bioinfo.imdik.pan.pl\/index.php\/wp-json\/wp\/v2\/media?parent=12"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}