Project: ATLAS-COVID-19


Project title:

Creating an atlas of interactions of bioactive compounds and peptides with the proteins and glycoproteins of the 2019-nCOV virus as well as with the human ACE2 protein, and the design of new inhibitors with potential activity against COVID-19

Research groups:

  • Bioinformatics Laboratory, Mossakowski Medical Research Centre Polish Academy of Sciences
  • Laboratory of Molecular Design and Bioinformatics, Faculty of Physics, University of Warsaw

Preliminary research:

  • Binding poses of 4 antiviral drugs (brecanavir, lopinavir, nelfinavir and saquinavir) in complex with  SARS-CoV-2 protease:

brecanavir lopinavir
nelfinavir saquinavir