Cardiovascular risk markers in dilated cardiomyopathy in Emery-Dreifuss muscular dystrophy (EDMD).

TitleCardiovascular risk markers in dilated cardiomyopathy in Emery-Dreifuss muscular dystrophy (EDMD).
Publication TypeJournal Article
Year of Publication2014
AuthorsNiebroj-Dobosz, Irena, Sokołowska Beata, Madej-Pilarczyk Agnieszka, Marchel Michał, and Hausmanowa-Petrusewicz Irena
JournalInt J Cardiol
Volume173
Issue2
Pagination324-5
Date Published2014 May 1
ISSN1874-1754
KeywordsBiological Markers, Cardiomyopathy, Dilated, Cardiovascular Diseases, Humans, Muscular Dystrophy, Emery-Dreifuss, Risk Factors
AbstractCardiovascular risk biomarkers help to define cardiac dysfunction, assist pharmacological therapy and select patients qualifying for cardiac device implantation and/or heart transplant. Some biomarkers are of value in detecting dilated cardiomyopathy (DCM) in Emery–Dreifuss muscular dystrophy (EDMD), a genetically transmitted deficiency of emerin (EDMD1) or lamin A/C (EDMD2). Clinical symptoms of EDMD manifest as skeletal muscle atrophy, joint contractures and dilated cardiomyopathy (DCM). The latter often remains clinically silent for a prolonged period, but finally might lead to sudden death.
DOI10.1016/j.ijcard.2014.03.058
Alternate JournalInt. J. Cardiol.
PubMed ID24681014